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In this issue of JEM, Shakiba et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20201966) tell a tale of three tumor infiltrating lymphocytes (TILs). The first TIL was too strong and became exhausted. The second TIL was too weak and became inert. The third TIL lost CD8, and this made it just right.

Original publication

DOI

10.1084/jem.20212269

Type

Journal article

Journal

J Exp Med

Publication Date

07/02/2022

Volume

219