Emerging Monkeypox Virus Sublineage C.1 Causing Community Transmission, Vietnam, 2023.
Hoa HTT., Dung NT., Hung LM., Hong NTT., Quy VT., Thao NT., Duy NT., Truong H., Hoang TM., Thanh NT., Phuoc MPH., Trung TN., Thong NN., Huy ND., Thoa VTK., Vuong VT., Tai NT., Nhung HK., Linh DP., Thoa PTN., Yen LM., Thien TB., Truc THC., Thanh LK., Ny NTH., Hoang VT., Ngoc NM., Man DNH., Thwaites L., Thanh TT., Chau NVV., Thwaites G., Anh NT., Van Tan L.
We studied a community cluster of 25 mpox cases in Vietnam caused by emerging monkeypox virus sublineage C.1 and imported into Vietnam through 2 independent events; 1 major cluster carried a novel APOBEC3-like mutation. Three patients died; all had advanced HIV co-infection. Viral evolution and its potential consequences should be closely monitored.