A platform for SpyCatcher conjugation to native antibodies

Krajcovicova S.; Wharton T.; Driscoll CL.; King TA.; Howarth MR.; Spring DR.

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A platform for SpyCatcher conjugation to native antibodies

Krajcovicova S., Wharton T., Driscoll CL., King TA., Howarth MR., Spring DR.

We introduce a platform for the conjugation of SpyCatcher proteins to native antibodies using cysteine-reactive tetra-divinylpyrimidine (TetraDVP)-SpyTag linkers.

Original publication

DOI

10.1039/d5sc02286j

Type

Journal article

Journal

Chemical Science

Publisher

Royal Society of Chemistry (RSC)

Publication Date

2025