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The surface coverage and subsequent arginine-glycine-aspartic acid (RGD) derivatization of the Ti-6Al-4V surface which can be readily effected by silanization in amounts far higher on a surface-bound Ti phosphate interface that can be accomplished on the native oxide by standard methods were shown. Nonetheless, the inherent hydrolytic instability under physiological conditions of surface siloxanes ultimately limits their utility. Thus, a successful surface chemistry approach for creating stable osteoconductive surfaces on Ti and Ti-6Al-4V was found.

Original publication

DOI

10.1021/la0203436

Type

Journal article

Journal

Langmuir

Publication Date

07/01/2003

Volume

19

Pages

200 - 204