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The subcapsular region of the kidney has frequently served as the site of choice for transplantation studies owing to a number of compelling reasons. High levels of vascularization provide a ready blood supply, whereas the subcapsular region itself can accommodate tissues of a range of size and sources. Historically, transplantation to this site has proven important for studies of both central and peripheral tolerance. Here, the transplantation technique and its major variations are described for broad application.

Original publication




Journal article


Methods Mol Biol

Publication Date





347 - 353


Animals, Islets of Langerhans Transplantation, Kidney, Transplantation, Heterotopic, Transplantation, Homologous