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In some cases vaccination is unreliable. For example vaccination against pertussis has comparatively high level of primary and secondary failures. To evaluate efficiency of vaccination we introduce the idea of effective vaccination rate and suggest an approach to estimate it. We consider pertussis in New Zealand as a case study. The results indicate that the level of immunity failure for pertussis is considerably higher than was anticipated.

Type

Journal article

Journal

J Theor Biol

Publication Date

21/09/2003

Volume

224

Pages

269 - 275

Keywords

Child, Endemic Diseases, Humans, Immunity, Models, Immunological, New Zealand, Time Factors, Treatment Failure, Vaccination, Whooping Cough