Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The synthesis of (2R,3R,4S,5R,6S)-3,4,5-trihydroxy-2-hydroxymethyl-7,9-diaza-oxaspiro-[ 4,5]decane-8,10-dione, a galactopyranose analogue of the powerful herbicide hydantocidin, is described. The compound caused no inhibition of the activity of a number of glucosyl or galactosyl transferases, or of α- or β-galactosidases. An azidoester containing a galactopyranosyl moiety may be a useful intermediate for the generation of libraries of compounds of galactose mimics.

Original publication

DOI

10.1016/0957-4166(95)00432-7

Type

Journal article

Journal

Tetrahedron Asymmetry

Publication Date

01/01/1996

Volume

7

Pages

157 - 170