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Responses to GLPhe5 were generated in vitro, using the GLPhe helper factor. A plaque assay, using GLPhe-coated SRC, was used to measure antibody responses to GLPhe. Mice of different H-2 haplotypes were tested for the ability to produce the GLPhe helper factor or to respond to a known GLPhe helper factor. We report here defects in nonresponder mice of different strains in both the production of helper factor and in the capacity to respond to it. © 1978 Springer-Verlag New York Inc.

Original publication

DOI

10.1007/BF01563938

Type

Journal article

Journal

Immunogenetics

Publication Date

01/12/1978

Volume

6

Pages

471 - 481