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A framework for quantitative analysis of the mechanisms underlying immunological synapse assembly has been recently developed. This model uses partial differential equations to describe the binding interactions of receptors and ligands, with the constraint that they are embedded in apposed deformable membranes linked to a cytoskeletal complex.


Journal article


Trends Immunol

Publication Date





500 - 502


Animals, Humans, Intercellular Junctions, Kinetics, Ligands, Mathematics, Models, Immunological, Receptors, Immunologic