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Dissecting the genetics of common, complex disorders remains one of the great challenges in human genetics. The acceleration of human genome sequence determination, improvements in informatics, large-scale identification of single nucleotide polymorphisms and improvements in scoring technologies have now increased the feasibility of identifying polymorphisms that predispose to common disease.


Journal article


Curr Opin Genet Dev

Publication Date





330 - 334


Chromosome Mapping, Genetic Diseases, Inborn, Genetics, Medical, Genome, Human, Humans, Polymorphism, Genetic