Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The sensitivity of Borrelia burgdorferi sensu lato to animal sera was analyzed. Complement-mediated borreliacidal effects were observed with particular combinations of host serum and Borrelia genospecies. The species-specific pattern of viability and/or lysis is highly consistent with the pattern of reservoir competence of hosts for B. burgdorferi sensu lato, suggesting a key role of complement in the global ecology of Lyme borreliosis.

Type

Journal article

Journal

Infect Immun

Publication Date

03/1998

Volume

66

Pages

1248 - 1251

Keywords

Animals, Bacteriolysis, Complement System Proteins, Cricetinae, Ecology, Humans, Lyme Disease, Mesocricetus, Mice, Mice, Inbred BALB C, Muridae, Species Specificity