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Certain immunological responses of 4-6 month old calves experimentally inoculated with either cytopathic or non-cytopathic bovine virus diarrhoea virus (BVDV) were compared with those of uninfected control calves. The tests used to demonstrate the immunological responses were the transformation of lymphocytes by PHA mitogen, the percentage of lymphocytes with surface immunoglobulin, and the antibody titres induced by an intravenous inoculation of killed Brucella abortus. There were no significant differences between the two groups of calves and therefore, the mild experimental disease produced by BVDV did not appear to affect adversely the immunological response.

Type

Journal article

Journal

Vet Immunol Immunopathol

Publication Date

12/1980

Volume

1

Pages

371 - 378

Keywords

Animals, Antibodies, Bacterial, Bovine Virus Diarrhea-Mucosal Disease, Brucella abortus, Cattle, Diarrhea Viruses, Bovine Viral, Immunoglobulins, Lymphocyte Activation, Phytohemagglutinins