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The replication cycles of a cytopathogenic and a non-cytopathogenic strain of bovine virus diarrhoea virus (BVDV) were similar in kinetics and the tendency of cell-free infectivity to exceed the titre of cell-associated, but differed in virus yield per cell. Actinomycin D enhanced the yield of the non-cytopathogenic strain and depressed that of the cytopathogenic strain.


Journal article


Arch Virol

Publication Date





365 - 369


Animals, Cattle, Cell Line, Cytopathogenic Effect, Viral, Dactinomycin, Diarrhea Viruses, Bovine Viral, Kinetics, Pestivirus, Virus Replication