Cytotoxic T-cell clones raised against X-31 (H3N2) influenza virus in C57BL/6 mice can be directed against an influenza A virus subtype specific determinant (1). A representative T-cell clone (A3.1) has been used in combination with a set of genetically typed recombinant viruses, to show that the A/PR/8/34 nucleoprotein can be responsible for cytotoxic T-lymphocyte recognition of infected target cells.

Type

Journal article

Journal

Virology

Publication Date

03/1984

Volume

133

Pages

456 - 459

Keywords

Animals, Clone Cells, Cloning, Molecular, Epitopes, Genes, Genes, Viral, H-2 Antigens, Influenza A virus, Mice, Mice, Inbred C57BL, Nucleoproteins, T-Lymphocytes, Cytotoxic