Cytotoxic-T-lymphocyte-inducing vaccines against malaria: A genetic approach
No effective vaccine is available for any parasitic disease of humans. The design of such a vaccine presents particular challenges but one new approach is based on the analysis of peptides bound to human leucocyte antigen (HLA) molecules. This approach has now been applied to identify components of a new cytotoxic-T-lymphocyte-inducing vaccine against malaria. A similar approach may be useful in designing vaccines against other complex pathogens.