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Tumor necrosis factor α (TNF-α) is a well-recognized proinflammatory cytokine, and as such provides an ideal target for anti-inflammatory therapies. Recent developments have shown very exciting results, and in this article, Jan Bondeson, Marc Feldman, and Ravinder N. Maini review the outcome of clinical trials of anti-TNF-α therapies in a range of chronic inflammatory diseases.


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136 - 140