AI-based method provides insights for predicting colorectal cancer outcomes
2 February 2024
The largest multiparameter immunoprofiling study in cancer to date has suggested an underappreciated role of a subset of immune cells in determining the risk of bowel cancer relapse after surgery.
Study uncovers how the Hepatitis B virus adapts
30 January 2024
A new hepatitis B study reveals how viruses adapt to low-oxygen environments, such as those found deep within the liver, opening up possible new therapeutic targets for liver pathogens. NDM researchers have identified hypoxia-inducible factors (HIFs) playing an important role in the regulation of editing of viral RNAs in low oxygen conditions.
UK minister meets with Oxford pandemic researchers
29 January 2024
Researchers at the Jenner Institute, the Oxford Vaccine Group and the Pandemic Sciences Institute hosted the Rt Hon Andrew Mitchell MP, Minister for Development and Africa, to the laboratories and clinics of several of its vaccine development groups.
MORU leads study testing a single pill for drug-resistant malaria in Africa and Asia
15 December 2023
To boost the fight against drug-resistant malaria parasites now emerging in Africa, researchers at the Mahidol Oxford Tropical Medicine Research Unit will study the safety and efficacy of a fixed-dose combination (FDC) containing three antimalarial drugs currently given to patients separately in a triple artemisinin-based combination therapy (TACT) cocktail.
VALIDATE network receives Medical Research Council grant
13 December 2023
An international network of researchers, led by NDM’s Professor Helen McShane and Professor Samantha Sampson from Stellenbosch University, has recently been awarded a new UK Medical Research Council (MRC) grant to continue the network activities until 2027.
Understanding how lipids influence immune responses
3 October 2023
In a study, recently published in the Cell, an international team of scientists, including CAMS Oxford Institute (COI) group leaders Professor Graham Ogg and Dr Yi-Ling Chen, has developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.
Tao Dong appointed the Brigitte (Ita) Askonas Professor of Translational Immunology
1 September 2023
With effect from 1st May 2023, Professor Tao Dong, has been appointed the Brigitte (Ita) Askonas Professor of Translational Immunology.
Women diagnosed with early breast cancer today are much less likely to die from the disease than 20 years ago
13 June 2023
The results of this observational study can help clinicians to estimate prognosis for patients diagnosed with breast cancer today.
Autoimmune disorders found to affect around one in ten people
9 May 2023
A new population-based study of 22 million people shows that autoimmune disorders now affect about one in ten individuals. The work, published in The Lancet, also highlights important socioeconomic, seasonal, and regional differences for several autoimmune disorders and provides new clues on possible causes behind these diseases.
Oxford expands the Cartography collaboration with Janssen
6 June 2022
The University of Oxford announced today that it has expanded a strategic collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson. The agreement was facilitated by Johnson & Johnson Innovation
Multiplex Serology: the first step towards looking at 20 infectious agents in half a million people
27 May 2022
Certain infectious agents are recognised causes of cancer and other chronic diseases. To understand the pathological mechanisms underlying such relationships, we designed a Multiplex Serology platform to measure quantitative antibody responses against 45 antigens from 20 infectious agents.
Outbreak: fighting coronavirus
13 February 2020
In a new Oxford Science Blog, Charvy Narain (Communications & Public Engagement Manager, Radcliffe Department of Medicine) talks to some of the Oxford University researchers coming together to fight the novel Coronavirus outbreak.
Researchers find new cells that repair tissue
18 September 2019
Researchers from Nuffield Department of Medicine have discovered that a newly discovered group of cells can help repair tissues in the body.
Rapidly spreading multidrug-resistant parasites render frontline malaria drug ineffective in southeast Asia
23 July 2019
A rapidly evolving multi-drug resistant lineage of P. falciparum malaria parasites continues to spread in South East Asia, leading to alarmingly high treatment failure rates in Cambodia, Thailand and Vietnam for DHA-piperaquine, one of the world’s most important anti-malaria drugs.
New study shows faster way to cure vivax malaria
19 July 2019
A large clinical trial in Africa and Asia has shown that a 7 day course of high dose primaquine, a drug used to treat P. vivax malaria, is well tolerated and just as effective as the current standard 14 day regimen, according to a study published this week in The Lancet. These findings have important implications for the treatment and elimination of vivax malaria in the Asia Pacific.
Award-winning citizen science project tackling TB gets millionth classification
5 October 2018
An award-winning Oxford-based international project to tackle antibiotic resistance has achieved its one millionth classification.
UK-led study marks shift towards genetic era in tackling TB
28 September 2018
In a landmark study that may herald a quicker, more tailored treatment for the millions of people around the world living with tuberculosis (TB), UK researchers have shown how our understanding of TB’s genetic code is now so detailed that we can now predict which commonly used anti-TB drugs are best for treating a patient’s infection and which are not.
MAIT cells protect against pulmonary Legionella longbeachae infection
23 August 2018
New paper published in Nature Communications from researchers in Respiratory Medicine Unit, NDM Experimental Medicine'
Malaria’s ticking time bomb
27 July 2018
Scientists are racing to stamp out the disease in Southeast Asia before unstoppable strains spread.